Helmisan 30 ml (Praziquantel+Pyrantel pamoate) Syringe-Tube

Composition

1 ml of the drug contains:

pyrantel pamoate — 300 mg

praziquantel – 20 mg

Description

The gel is light yellow, homogeneous, odorless.

Pharmacological properties

Pyrantel pamoate is a pyrimidine derivative. Acts on roundworms (adults and 4th stage larvae) as a depolarizing muscle relaxant that causes neuromuscular blockade, causing death of nematodes.

Praziquantel is a quinoline derivative. Increases the permeability of cell membranes for calcium ions in cestodes and trematodes, which leads to generalized muscle contraction, paralysis of helminths and their death. Causes vacuolization and damage to the epithelium of parasites, as a result of which they become sensitive to enzymes of the gastrointestinal tract.

Indication

Prevention and treatment  of horses, ponies, kulans, Przewalski’s horses affected by endo- and ectoparasites:

• nematodes of the family Ascaridae, Strongylidae, Cyathostomidae (Trihonematidae), Strongyloididae, Oxyuridae, Spiruridae;
• cestodes of the Anoplocephalidae family;
• trematodes of the families Schistosomatidae, Dicrocoeliidae;
• by the larvae of gastropods Gasterophilus spp.

Contraindication

Do not prescribe to clinically sick and exhausted animals, females in the last week of pregnancy.

 

Method of application and dosage

The drug is administered using a syringe-tube on the root of the tongue, once. In case of infestations caused by Trihostrongylus axei larvae, twice a day. The therapeutic and prophylactic dose is 1 g per 20 kg of body weight.

Preventive deworming of adult horses is carried out once every 3-4 months.

For deworming of wild animals, the calculated dose is mixed with moistened compound feed and fed during morning feeding individually or by group method.

Reservation

After the last use of the drug, animals can be slaughtered for meat after 7 days. Meat obtained before the specified term is disposed of or fed to non-productive animals, depending on the opinion of the veterinarian.

Storage conditions

In a dry place protected from direct sunlight, inaccessible to children, at temperatures from +1 to +25 °C.

Expiration date

2 years.